Windows are a significant path for structure-borne and air-borne noise transmission in general aviation aircraft. In this paper, numerical and experimental results are used to evaluate damped plexiglas windows for the reduction of structure-borne and air-borne noise transmitted into the interior of an aircraft. In contrast to conventional homogeneous windows, the damped plexiglas windows were fabricated using two or three layers of plexiglas with transparent viscoelastic damping material sandwiched between the layers. Transmission loss and radiated sound power measurements were used to compare different layups of the damped plexiglas windows with uniform windows of the same nominal thickness. This vibro-acoustic test data was also used for the verification and validation of finite element and boundary element models of the damped plexiglas windows. Numerical models are presented for the prediction of radiated sound power for a point force excitation and transmission loss for diffuse acoustic excitation. Radiated sound power and transmission loss predictions are in good agreement with experimental data. Once validated, the numerical models were used to perform a parametric study to determine the optimum configuration of the damped plexiglas windows for reducing the radiated sound power for a point force excitation.